PAWR anticorps
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- Antigène Voir toutes PAWR Anticorps
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAWR est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Reacts with Human 36 kDa Par-4 protein.
- Purification
- Affinity Chromatography on Protein A
- Immunogène
- Synthetic peptide derived from internal domain of Human Par-4.
- Top Product
- Discover our top product PAWR Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Restore in distilled water.
- Buffer
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- Autre désignation
- PAR4 / PAWR (PAWR Produits)
- Synonymes
- anticorps MGC81382, anticorps pawrl, anticorps zgc:103513, anticorps PAWR, anticorps PAR4, anticorps Par-4, anticorps Par4, anticorps 2310001G03Rik, anticorps pro-apoptotic WT1 regulator, anticorps PRKC, apoptosis, WT1, regulator L homeolog, anticorps PRKC, apoptosis, WT1, regulator, anticorps PAWR, anticorps pawr.L, anticorps pawr, anticorps Pawr
- Sujet
- Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.Synonyms: PRKC apoptosis WT1 regulator protein, Par-4, Prostate apoptosis response 4 protein
- ID gène
- 5074
- NCBI Accession
- NP_002574
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