RAG1 anticorps (C-Term)

N° du produit ABIN1108824

Détail du produit anti-RAG1 anticorps

Antigène: RAG1 (Recombination Activating Gene 1 (RAG1))

Épitope: C-Term

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAG1 est non-conjugé

Application: Western Blotting (WB)

Séquence: IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT

Réactivité croisée (Details): Species reactivity (tested):Human, mouse.

Purification: Immunoaffinity column

Immunogène: Synthetic peptide corresponding to a near C-terminal region of mouse

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur RAG1

Antigène: RAG1 (Recombination Activating Gene 1 (RAG1))

Autre désignation: RAG1 / RNF74 (RAG1 Produits)

Synonymes: anticorps RAG-1, anticorps rag1, anticorps RNF74, anticorps Rag-1, anticorps rag-1, anticorps rag1a, anticorps recombination activating 1, anticorps recombination activating gene 1, anticorps recombination activating gene 1 S homeolog, anticorps Rag1, anticorps RAG1, anticorps rag1, anticorps rag1.S

Sujet: As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.Synonyms: RAG-1, RING finger protein 74, V(D)J recombination-activating protein 1

Poids moléculaire: RAG1: 119 kDa

ID gène: 19373

NCBI Accession: NM_009019