Surfactant Protein C anticorps (N-Term)

N° du produit ABIN1108993

Détail du produit anti-Surfactant Protein C anticorps

Antigène: Surfactant Protein C (SFTPC)

Épitope: AA 1-33, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Surfactant Protein C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody detects pro-SP-C (AA 1-33).

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Purified

Immunogène: Recombinant human pro-SP-C (AA 1-33), GST fusion

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur Surfactant Protein C

Antigène: Surfactant Protein C (SFTPC)

Autre désignation: SFTPC (SFTPC Produits)

Synonymes: anticorps SFTPC, anticorps SPC, anticorps SP-C, anticorps psp-c, anticorps sftp2, anticorps xSP-C, anticorps Bricd6, anticorps SP5, anticorps Sftp-2, anticorps Sftp2, anticorps pro-SpC, anticorps BRICD6, anticorps PSP-C, anticorps SFTP2, anticorps SMDP2, anticorps surfactant protein C, anticorps surfactant, pulmonary-associated protein C S homeolog, anticorps surfactant, pulmonary-associated protein C, anticorps surfactant associated protein C, anticorps SFTPC, anticorps sftpc.S, anticorps sftpc, anticorps Sftpc

Sujet: There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-C is a 34-35 amino acid peptide, of 4 kD that is proteolytically processed from a 21 kD precursor protein. SP-C is initiated early in the embryogenic period of lung formation, where SP-C transcripts are detected uniformly in epithelial cells lining the primitive airways. During lung development SP-C expression is decreased in cells of the proximal conducting portion of the lung. Ultimately SP-C is expressed selectively in type II epithelial cells in the alveolus of the lung. SP-C is secreted into the airspace where it enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-C plays an important role in the spreading and stabilization of phospholipid films in the alveolus. SP-C is essential for air-breathing in mammals and is therefore largely conserved. Deficiency of SP-C and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: Pulmonary surfactant-associated protein C, Pulmonary surfactant-associated proteolipid SPL(Val), SFTP2, SP-C, SP5, Surfactant protein C

ID gène: 6440

NCBI Accession: NP_001165828

UniProt: P11686