SLC17A7 anticorps (C-Term)

N° du produit ABIN1109031

Détail du produit anti-SLC17A7 anticorps

Antigène: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC17A7 est non-conjugé

Application: Western Blotting (WB), Immunoelectron Microscopy (IEM), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts with Rat 55-60 kDa VGLUT1 protein of BON cells stably expressing VGLUT1 and of total Rat brain extracts. No cross reactivity was detected with VGLUT2 and VGLUT3.

Réactivité croisée (Details): Species reactivity (tested):Rat.

Purification: Antigen Affinity Chromatography

Immunogène: A 17 residue synthetic peptide derived from C-terminal domain of Rat. Remarks: Vesicular Glutamate Transporter Type 1 (MW : 55-60 kD).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 0.1 M Tris, 0.1 M Glycine, Glycerol 50 % , pH 7.8, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SLC17A7

Antigène: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Autre désignation: SLC17A7 / VGLUT1 (SLC17A7 Produits)

Synonymes: anticorps 2900052E22Rik, anticorps AI851913, anticorps VGluT1, anticorps Vglut1, anticorps BNPI, anticorps VGLUT1, anticorps slc17a7, anticorps vglut1, anticorps solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, anticorps solute carrier family 17 member 7, anticorps solute carrier family 17 (vesicular glutamate transporter), member 7a, anticorps Slc17a7, anticorps SLC17A7, anticorps slc17a7a

Sujet: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.Synonyms: BNPI, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7, Vesicular glutamate transporter 1

ID gène: 116638

NCBI Accession: NP_446311