TIMP3 anticorps (C-Term)

N° du produit ABIN1109258

Détail du produit anti-TIMP3 anticorps

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP3 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects TIMP3 (C-term). No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: A peptide mapping at the C-terminal end of TIMP-3 of human origin .Remarks: Sequence is different to the related rat sequence by single amino acid.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TIMP3

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Autre désignation: TIMP3 (TIMP3 Produits)

Synonymes: anticorps TIMP-3, anticorps TIMP3, anticorps timp3, anticorps HSMRK222, anticorps K222, anticorps K222TA2, anticorps SFD, anticorps IMP-3, anticorps timp3-A, anticorps Timp-3, anticorps metalloproteinase inhibitor 3, anticorps TIMP metallopeptidase inhibitor 3, anticorps Metalloproteinase inhibitor 3, anticorps TIMP metallopeptidase inhibitor 3 L homeolog, anticorps tissue inhibitor of metalloproteinase 3, anticorps CpipJ_CPIJ003282, anticorps TIMP3, anticorps timp3, anticorps Timp3, anticorps timp3.L

Sujet: The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).Synonyms: Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3, Tissue inhibitor of metalloproteinases 3

ID gène: 7078

NCBI Accession: NP_000353

UniProt: P35625