anticorps TIMP4, anticorps TIMP-4, anticorps timp4, anticorps TIMP metallopeptidase inhibitor 4, anticorps TIMP metallopeptidase inhibitor 4, tandem duplicate 3, anticorps tissue inhibitor of metalloproteinase 4, anticorps TIMP4, anticorps timp4.3, anticorps Timp4
Sujet
The tissue inhibitors of metalloproteinases (TIMPs) inhibit matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP4 gene contains 5 exons that span 6 kb of genomic DNA.The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 gene is mapped to chromosome 3p25. TIMP-4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.Synonyms: Metalloproteinase inhibitor 4, TIMP-4, Tissue inhibitor of metalloproteinases 4