TRAFD1 anticorps (C-Term)

N° du produit ABIN1109296

Détail du produit anti-TRAFD1 anticorps

Antigène: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAFD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: TATNHVTEGI PRLDSQPQET SPELPRRRVR HQGDLSSGYL DDTKQETANG

Réactivité croisée (Details): Species reactivity (expected):Rat, Mouse, Dog, BovineSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: The immunogen for anti-TRAFD1 antibody: synthetic peptide directed towards the C terminal of human TRAFD1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur TRAFD1

Antigène: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Autre désignation: TRAFD1 / FLN29 (TRAFD1 Produits)

Synonymes: anticorps MGC80116, anticorps fln29, anticorps MGC89491, anticorps TRAFD1, anticorps 1110008K06Rik, anticorps Fln29, anticorps FLN29, anticorps TRAF-type zinc finger domain containing 1, anticorps TRAF-type zinc finger domain containing 1 L homeolog, anticorps TRAF-type zinc finger domain-containing protein 1, anticorps TRAF type zinc finger domain containing 1, anticorps TRAFD1, anticorps trafd1.L, anticorps trafd1, anticorps trad1, anticorps Trafd1

Sujet: TRAFD1 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways and may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. TRAFD1 may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.Synonyms: TRAF-type zinc finger domain-containing protein 1

ID gène: 10906

NCBI Accession: NP_006691