IL-1 beta anticorps

N° du produit ABIN114529

Cet anticorps Souris Monoclonal détecte spécifiquement IL-1 beta dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL-1 beta anticorps (ABIN114529)

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-1 beta est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: S1H12

Détail du produit anti-IL-1 beta anticorps

Specificité: Reactive with natural and recombinant human IL-1β. Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β.

Purification: Protein G affinity purified

Immunogène: Purified recombinant human IL-1beta

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot: An antibody concentration of 20-100 ng/mL will allow visualization of 100 ng/lane of human IL-1β.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur IL-1 beta

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Autre désignation: Interleukin-1 beta / IL-1B

Sujet: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2

ID gène: 3553

NCBI Accession: NP_000567

UniProt: P01584

Pathways: Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome