FLT1 anticorps (Extracellular Domain)

N° du produit ABIN115153

Détail du produit anti-FLT1 anticorps

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Épitope: Extracellular Domain

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1. It cross reacts with Mouse Flt-1 (e.g. natural occurring soluble Mouse Flt-1) in Western blot analysis (Figure 1).

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Protein G Chromatography

Immunogène: Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)

Clone: FLTEWI (EWI)

Isotype: IgG1

Information d'application

Indications d'application: ELISA (1.5-8 μg/mL). Western blotting (1-10 μg/mL). Immunoprecipitation (1-5 μg/mL lysate or reaction volume). Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FLT1

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Autre désignation: VEGFR-1 / Flt-1 (FLT1 Produits)

Synonymes: anticorps FLT, anticorps FLT-1, anticorps VEGFR-1, anticorps VEGFR1, anticorps FLT1, anticorps flt1b, anticorps sFlt1, anticorps AI323757, anticorps Flt-1, anticorps fms related tyrosine kinase 1, anticorps FMS-related tyrosine kinase 1, anticorps vascular endothelial growth factor receptor 1, anticorps fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), anticorps FMS-like tyrosine kinase 1, anticorps vascular endothelial growth factor receptor-1, anticorps FLT1, anticorps Flt1, anticorps CpipJ_CPIJ012087, anticorps flt1, anticorps FLT-1

Sujet: VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor

ID gène: 2321

NCBI Accession: NP_001153392

UniProt: P17948

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals