TNFSF13 anticorps (Biotin)

N° du produit ABIN116392

Détail du produit anti-TNFSF13 anticorps (Biotin)

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF13 est conjugé à/à la Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts with APRIL.

Purification: Affinity chromatography.

Immunogène: Highly pure (>98%) recombinant hAPRIL.

Information d'application

Indications d'application: Elisa(Direct): To detect hAPRIL by direct ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2- 0.4 ng/well of recombinant hAPRIL. (Sandwich): To detect hAPRIL by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with Polyclonal Anti-Human APRIL (PP1200P) as a captureantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hAPRIL. Western Blot: To detect hAPRIL by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hAPRIL is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur TNFSF13

Antigène: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Autre désignation: CD256 / APRIL (TNFSF13 Produits)

Synonymes: anticorps APRIL, anticorps CD256, anticorps TALL-2, anticorps TALL2, anticorps TRDL-1, anticorps ZTNF2, anticorps 2310026N09Rik, anticorps April, anticorps Tall2, anticorps Trdl1, anticorps SLAN, anticorps ANP32B, anticorps april, anticorps tnf13, anticorps TNLG7B, anticorps TNF superfamily member 13, anticorps tumor necrosis factor (ligand) superfamily, member 13, anticorps acidic leucine-rich nuclear phosphoprotein 32 family member B, anticorps TNFSF13, anticorps Tnfsf13, anticorps LOC494442, anticorps tnfsf13

Sujet: APRIL (A PRoliferation Inducing Ligand) a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. Members of the TNF superfamily regulate immune responses and induce apoptosis. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.Synonyms: A proliferation-inducing ligand, TALL-2, TALL2, TNF- and APOL-related leukocyte expressed ligand 2, TNF-related death ligand 1, TNFSF13, TRDL-1, Tumor necrosis factor ligand superfamily member 13, ZTNF2

ID gène: 8741

NCBI Accession: NP_003799

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response