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LAG3 anticorps (N-Term)

LAG3 Reactivité: Humain ICC Hôte: Souris Monoclonal 17B4 unconjugated

N° du produit ABIN1169109

Fiche de données

Antigène Voir toutes LAG3 Anticorps

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
Épitope
15

14

9

7

7

4

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivité
88

39

10

5

4

2

1

1

1
Humain
Hôte
52

35

12

4
Souris
Anticorps secondaires appropriés
Clonalité
53

47

1
Monoclonal
Conjugué
53

7

6

4

4

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp LAG3 est non-conjugé
Application
69

36

33

30

25

22

15

13

13

10

10

6

5

2

2

1

1

1

1

1

1

1

1
Immunocytochemistry (ICC)

Specificité

Recognizes human LAG-3.

Réactivité croisée

Humain

Pureté

>95 % (SDS-PAGE)

Immunogène

Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Clone

17B4

Isotype

IgG1

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anti-Lymphocyte-Activation Gene 3 (LAG3) antibody
LAG3 Reactivité: Humain WB, ELISA, IHC, FACS, ICC, Neut Hôte: Souris Monoclonal 3A4A10 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibody
LAG3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibody
LAG3 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 8B12E10 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (N-Term) antibody
LAG3 Reactivité: Humain WB, ELISA, IHC, IP, FACS, ICC Hôte: Souris Monoclonal L4-PL33 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibody
LAG3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 244-487) antibody
LAG3 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibody
LAG3 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibody
LAG3 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibody
LAG3 Reactivité: Humain, Souris WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc) Hôte: Lapin Polyclonal unconjugated

Indications d'application

Optimal working dilution should be determined by the investigator.

Commentaires

New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 590 shows bright red fluorescence (lambdaabs (max): 594nm, lambdaem (max): 624nm, epsilonmax: 120'000).

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

In PBS containing 0.02 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C

Stockage commentaire

Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Date de péremption

12 months
Antigène

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation

LAG-3 (LAG3 Produits)

Synonymes

anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3

Sujet

Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt

P18627

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints