TNFRSF10A anticorps (Atto 488)
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- Antigène Voir toutes TNFRSF10A Anticorps
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TNFRSF10A est conjugé à/à la Atto 488
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificité
- Recognizes human TRAIL-R1.
- Réactivité croisée
- Humain
- Réactivité croisée (Details)
- Does not cross-react with human TRAIL-R2, -R3 or -R4.
- Purification
- Purified from concentrated hybridoma tissue culture supernatant.
- Pureté
- >95 % (SDS-PAGE)
- Immunogène
- Recombinant human TRAIL-R1 (DR4).
- Clone
- HS101
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF10A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. - Date de péremption
- 12 months
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- Antigène
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Autre désignation
- TRAIL-R1 (TNFRSF10A Produits)
- Synonymes
- anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798
- Sujet
- TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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