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TNFRSF10A anticorps

TNFRSF10A Reactivité: Humain FACS, IP, ICC, Func Hôte: Souris Monoclonal HS101 unconjugated
N° du produit ABIN1169236
  • Antigène Voir toutes TNFRSF10A Anticorps
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Reactivité
    • 88
    • 5
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 41
    Souris
    Clonalité
    • 49
    • 39
    Monoclonal
    Conjugué
    • 48
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNFRSF10A est non-conjugé
    Application
    • 44
    • 32
    • 25
    • 19
    • 17
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
    Specificité
    Recognizes human TRAIL-R1.
     Réactivité croisée
    Humain
    Réactivité croisée (Details)
    Does not cross-react with human TRAIL-R2, -R3 or -R4.
    Purification
    Purified from concentrated hybridoma tissue culture supernatant.
    Pureté
    >95 % (SDS-PAGE)
    Immunogène
    Recombinant human TRAIL-R1 (DR4).
    Clone
    HS101
    Isotype
    IgG1
    Top Product
    Discover our top product TNFRSF10A Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Antigène
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Autre désignation
    TRAIL-R1 (TNFRSF10A Produits)
    Synonymes
    anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798
    Sujet
    TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
    UniProt
    O00220
    Pathways
    Apoptose, Positive Regulation of Endopeptidase Activity
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