IL-8 anticorps

N° du produit ABIN1177284

Cet anticorps anti-IL-8 est un anticorps Souris Monoclonal détectant IL-8 dans WB, ELISA et Neut. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour IL-8 anticorps (ABIN1177284)

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-8 est non-conjugé

Application: Western Blotting (WB), ELISA, Neutralization (Neut)

Clone: 2A2

Détail du produit anti-IL-8 anticorps

Marque: BD Pharmingen™

Attributs du produit: Neutralization Activity: This antibody has been reported to be useful for the neutralization of recombinant human IL-8. Neutralization activity may be measured with a calcium flux assay using 250 ng/mL recombinant human IL-8 (Cat. No. 554609) to stimulate calcium mobilization in 1x10^7 cells/mL human lysed whole blood as indicator cells. Preincubation of the antibody with recombinant human IL-8 can neutralize calcium mobilization.
50% Neutralization (ND50) at 8 - 10 myg/mL
>95% Neutralization at 150 - 500 myg/mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Immunogène: Recombinant human IL-8

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-IL-8 (ABIN1177284)

Matsushima, Oppenheim: "Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF." dans: Cytokine, Vol. 1, Issue 1, pp. 2-13, (1991) (PubMed).

Détails sur IL-8

Antigène: IL-8 (IL8) (Interleukin 8 (IL8))

Autre désignation: IL-8

Sujet: The 2A2 antibody reacts with both the 72 and 77 amino acid forms of human IL-8. The immunogen used to produce the 2A2 hybridoma was E. coli-expressed recombinant human IL-8 (77 amino acid form). This antibody has been reported to show no cross-reactivity with the following cytokines or chemokines: Human IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-12 (p40 or p70), IL-13, IL-15, eotaxin, GRO, IFN- gamma, MCP-1, MCP-2, MCP-3, MIP-1alpha, MIP-1beta, NAP-2, PF4, RANTES, SCF, TNF, LT-alpha.

Pathways: Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy