TLR4 anticorps (Biotin)

N° du produit ABIN119328

Cet anticorps anti-TLR4 Monoclonal Souris conjugué à Biotin (Clone HTA125) (ABIN119328) détecte spécifiquement TLR4 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Chien, Porc, Cobaye et Singe.

Aperçu rapide pour TLR4 anticorps (Biotin) (ABIN119328)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain, Chien, Porc, Cobaye, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: HTA125

Détail du produit anti-TLR4 anticorps (Biotin)

Purification: Affinity chromatography on Protein G

Immunogène: Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: CD284 / TLR4

Sujet: TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4

NCBI Accession: NM_138554

UniProt: O00206

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins