IL-1 beta anticorps

N° du produit ABIN119945

L’anticorps anti-IL-1 beta Monoclonal Souris est utilisé pour la détection de IL-1 beta dans des échantillons de Porc. Il a été validé pour WB.

Aperçu rapide pour IL-1 beta anticorps (ABIN119945)

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivité: Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-1 beta est non-conjugé

Application: Western Blotting (WB)

Clone: DF8

Détail du produit anti-IL-1 beta anticorps

Specificité: This antibody is specific for Interleukin-1 beta (IL-1 beta).

Purification: Affinity Chromatography on Protein G

Immunogène: Recombinant Porcine IL-1 beta.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1 μg/mL - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.015 EU/ug

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS without stabilizer and preservative

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur IL-1 beta

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Autre désignation: Interleukin-1 beta / IL-1B

Sujet: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence. IL-1 beta is principally expressed by macrophages, and plays an important immunomodulatory role in the porcine immune response.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2

ID gène: 397122

NCBI Accession: NP_999220

UniProt: P26889

Pathways: Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome