IL2 Receptor beta anticorps

N° du produit ABIN120200

Détail du produit anti-IL2 Receptor beta anticorps

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL2 Receptor beta est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificité: This antibody recognises the CD122 cell surface glycoprotein. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. We recommend the use of SM2224LE for this purpose.

Purification: Affinity chromatography on Protein G

niveau d'endotoxine: Low Endotoxin

Immunogène: Cells from murine IL-2RB+ transformant TART-mBeta. Lymph node (cells from immunised Sprague Dawley rats were fused with cells of the mouse PA1 myeloma cell line.

Clone: TM-BETA1

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C to -70 °C.

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: CD122 / IL2RB (IL2RB Produits)

Synonymes: anticorps IL2RB, anticorps il-2rb, anticorps CD122, anticorps IL15RB, anticorps P70-75, anticorps IL2RBC, anticorps IL-15Rbeta, anticorps IL15Rbeta, anticorps Il-2/15Rbeta, anticorps Il-2Rbeta, anticorps p70, anticorps interleukin 2 receptor subunit beta, anticorps interleukin-2 receptor subunit beta, anticorps interleukin 2 receptor, beta, anticorps interleukin 2 receptor, beta chain, anticorps IL2RB, anticorps LOC510185, anticorps il2rb, anticorps Il2rb

Sujet: CD122 is a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75

ID gène: 16185

NCBI Accession: NP_032394

UniProt: P16297

Pathways: Signalistation JAK/STAT, Growth Factor Binding