IL-1 beta anticorps
Aperçu rapide pour IL-1 beta anticorps (ABIN121867)
Antigène
Voir toutes IL-1 beta (IL1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Synonyms: IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin
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Purification
- Affinity chromatography on protein G
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Immunogène
- Recombinaint chicken IL-1
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Indications d'application
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ELISA. Western Blot: This antibody detects a band of approximately 29 kDa in HD-11 cell lysatestransfected with chIL-1. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- Interleukin-1 beta / IL-1B
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Sujet
- IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
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ID gène
- 3553
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UniProt
- P01584
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène
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