IFNB1 anticorps

N° du produit ABIN121882

Cet anticorps Lapin Polyclonal détecte spécifiquement IFNB1 dans WB, IP et Func. Il présente une réactivité avec des échantillons de Poulet.

Aperçu rapide pour IFNB1 anticorps (ABIN121882)

Antigène: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reactivité: Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNB1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Détail du produit anti-IFNB1 anticorps

Specificité: This antibody recognizes Interferon beta (chIFN-beta). This antibody does not cross react with IFN gamma. This antiserum neutralizes chIFN-beta and can be used to discriminate IFN alpha and IFN beta bioactivities.

Attributs du produit: Synonyms: IFN-beta, IFNB1, IFB, Fibroblast interferon

Purification: Affinity chromatography on protein G

Immunogène: Recombinant chicken Interferon Beta

Information d'application

Indications d'application: Immunoprecipitation. Western Blot: This antibody detects a band of approximately 20 kDa. Funktional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IFNB1

Antigène: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Autre désignation: IFNB / Interferon beta

Sujet: Reports suggest that chIFN exhibits properties similar to mammalian IFN type I (IFNI). Functional studies revealed the presence of two distantly related IFNI genes, designated as IFN alpha and IFN beta, found on chicken chromosome Z. The serological distinction between these two IFNs has been verified using neutralisation assays, and there is evidence that the antiviral activity of chIFN-beta is approximately tenfold less compared to chIFN-alpha. This would suggest that chIFNbeta might have a different physiological role, though chIFN-beta is expressed strongly in virus-infected cells.Synonyms: Fibroblast interferon, IFB, IFN-beta, IFNB1

ID gène: 554219

UniProt: Q90873

Pathways: Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome