NR2E3 anticorps

N° du produit ABIN122365

Détail du produit anti-NR2E3 anticorps

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2E3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with Photoreceptor-Specific Nuclear Receptor (PNR/NR2E3) (family: NHR, subfamily: NR2 Hepatocyte NF4-like). BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 7 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.01 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur NR2E3

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Autre désignation: NR2E3 (NR2E3 Produits)

Synonymes: anticorps ESCS, anticorps PNR, anticorps RNR, anticorps RP37, anticorps rd7, anticorps LOC100228348, anticorps A930035N01Rik, anticorps wu:fj55b07, anticorps zgc:103631, anticorps nuclear receptor subfamily 2 group E member 3, anticorps nuclear receptor subfamily 2, group E, member 3, anticorps NR2E3, anticorps Nr2e3, anticorps nr2e3

Sujet: Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.Synonyms: Nuclear receptor subfamily 2 group E member 3, PNR, Photoreceptor-specific nuclear receptor, RNR, Retina-specific nuclear receptor

ID gène: 10002

UniProt: Q9Y5X4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway