PTGDR anticorps (Extracellular Domain)

N° du produit ABIN122373

Détail du produit anti-PTGDR anticorps

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Épitope: Extracellular Domain

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGDR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with Prostaglandin D2 Receptor (family: GPCR, subfamily: Prostanoid).

Purification: Peptide Immunogen Affinity Chromatography.

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with Formalin Fixed Paraffin Embedded Tissues: 4-7 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min, Remove from heat and let stand at room temperature in buffer for 20 min, Rinse in 1x TBS with Tween (TBST) for 1 min at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.7 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to 70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-PTGDR (ABIN122373)

Dash, Ghatak, Topi, Satapathy, Ek, Hellman, Olsson, Mehdawi, Sjölander: "High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model." dans: British journal of cancer, Vol. 126, Issue 4, pp. 586-597, (2022) (PubMed).

Détails sur PTGDR

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Autre désignation: PTGDR (PTGDR Produits)

Synonymes: anticorps AS1, anticorps ASRT1, anticorps DP, anticorps DP1, anticorps PTGDR1, anticorps Ptgdr, anticorps Ptgdr2, anticorps PTGDR, anticorps PGD, anticorps prostaglandin D2 receptor, anticorps prostaglandin D receptor, anticorps PTGDR, anticorps Ptgdrl, anticorps Ptgdr

Sujet: The prostaglandin D2 receptor is a Prostanoid Receptor that binds prostaglandin D2. Studies suggest that this receptor may be involved in vision, mucous secretion, myometrial relaxation, and asthmatic response. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries.Synonyms: ASRT1, PGD receptor, PGD2 receptor, Prostaglandin D2 receptor, Prostanoid DP receptor

ID gène: 5729

UniProt: Q13258

Pathways: Thromboxane A2 Receptor Signaling