JNK2 anticorps

N° du produit ABIN126823

Cet anticorps Souris Monoclonal détecte spécifiquement JNK2 dans WB, EIA et IHC (fro). Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour JNK2 anticorps (ABIN126823)

Antigène: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JNK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 12C5

Détail du produit anti-JNK2 anticorps

Specificité: This antibody specifically interacts with the N-terminus of SAPK1α/jnk2 kinases.

Attributs du produit: Synonyms: JNK-55, PRKM9, MAP kinase 9, Mitogen-activated protein kinase 9, Stress-activated proteinkinase JNK2, c-Jun N-terminal kinase 2

Purification: Subsequent thiophilic adsorbtion and Size Exclusion Chromatography

Ingrédients: incl. positive Control

Immunogène: Synthetic peptide conjugated to KLH.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.05 μg/mL. Immunohistochemistry on frozen sections. Positive Control: Cell lysate from untreated A431 cells. (See Protocol)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protocole: Positive Control Cell Lysate (A431 Untreated)

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL H2O (15 min, RT).

Buffer: 1 mLPBS containing 0.09 % Sosium Azide, PEG and Sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur JNK2

Antigène: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Autre désignation: MAPK9 / JNK2

Sujet: Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines. The SAPK1/jnk family consists of 3 isoforms: SAPK1α/jnk2, SAPK1β/jnk3, SAPK1γ/jnk1.Synonyms: JNK-55, MAP kinase 9, Mitogen-activated protein kinase 9, PRKM9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2

Poids moléculaire: 54 kDa

ID gène: 5601

UniProt: P45984

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins