SERPINB9 anticorps

N° du produit ABIN126942

Détail du produit anti-SERPINB9 anticorps

Antigène: SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SERPINB9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: The antibody clone PI9-17 recognizes 42 kDa native PI-9 and the 63 kDa PI-9 complexed to Granzyme B.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: PI9, Serpin B9, Cytoplasmic antiproteinase 3, CAP-3, CAP3, Proteinase inhibitor 9

Purification: Affinity Chromatography

Immunogène: Recombinant human full length PI9

Clone: PI9-17

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 2-4 μg/mL. Immunohistochemistry: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SERPINB9

Antigène: SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))

Autre désignation: SERPINB9 (SERPINB9 Produits)

Synonymes: anticorps SERPINB9, anticorps BB283241, anticorps CAP-3, anticorps CAP3, anticorps PI-9, anticorps PI9, anticorps Spi6, anticorps ovalbumin, anticorps serpin family B member 9, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 9, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 9, anticorps Serpinb9, anticorps SERPINB9

Sujet: Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.Synonyms: CAP-3, CAP3, Cytoplasmic antiproteinase 3, PI-9, PI9, Proteinase inhibitor 9, Serpin B9

ID gène: 5272

UniProt: P50453