TLR4 anticorps
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- Antigène Voir toutes TLR4 Anticorps
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TLR4 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificité
- This antibody detects TLR4.
- Purification
- Affinity Chromatography on Protein A.
- Immunogène
- Recombinant Human TLR4
- Top Product
- Discover our top product TLR4 Anticorps primaire
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- Indications d'application
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Western Blot: 0.5-4 μg/mL. Flow Cytometric analysis of cell surface expression of TLR4.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- PBS, pH 7.2 containing 50 % Glycerol, 1 % BSA as stabilizers and 0.02 % Thimerosal as preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Antigène
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Autre désignation
- CD284 / TLR4 (TLR4 Produits)
- Synonymes
- anticorps ARMD10, anticorps CD284, anticorps TLR-4, anticorps TOLL, anticorps Lps, anticorps Ly87, anticorps Ran/M1, anticorps Rasl2-8, anticorps toll like receptor 4, anticorps toll-like receptor 4, anticorps TLR4, anticorps Tlr4
- Sujet
- TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.Synonyms: Toll-like receptor 4
- NCBI Accession
- NM_138554
- UniProt
- O00206
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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