SPTAN1 anticorps

N° du produit ABIN127066

Détail du produit anti-SPTAN1 anticorps

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTAN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity Chromatography

Immunogène: Synthetic peptide surrounding amino acid 162 of Mouse alpha-Fodrin.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage .

Détails sur SPTAN1

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Autre désignation: Spectrin alpha Chain (Brain) / SPTAN1 (SPTAN1 Produits)

Synonymes: anticorps im:7157190, anticorps wu:fa20e05, anticorps wu:fb33g08, anticorps wu:fk32a10, anticorps zgc:112229, anticorps 2610027H02Rik, anticorps Spna-2, anticorps Spna2, anticorps EIEE5, anticorps NEAS, anticorps SPTA2, anticorps A2a, anticorps IPF, anticorps SPECA, anticorps spectrin alpha, non-erythrocytic 1, anticorps spectrin, alpha, non-erythrocytic 1, anticorps SPTAN1, anticorps sptan1, anticorps Sptan1

Sujet: Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of α-Fodrin leads to membrane malfunction and cell shrinkage.Synonyms: Alpha-II spectrin, Fodrin alpha chain, SPTA2, Spectrin non-erythroid alpha chain

ID gène: 10090

UniProt: P16546

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization