Integrin Alpha2b anticorps (FITC)

N° du produit ABIN127332

Cet anticorps anti-Integrin Alpha2b est un anticorps Souris Monoclonal détectant Integrin Alpha2b dans FACS, IF et IHC (fro). Adapté pour Humain.

Aperçu rapide pour Integrin Alpha2b anticorps (FITC) (ABIN127332)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SZ-22

Détail du produit anti-Integrin Alpha2b anticorps (FITC)

Attributs du produit: Molar Ratio: 15-25 moles of FITC per mole Ig.

Purification: Ion Exchange or Affinity Chromatography.

Immunogène: Washed Human platelets. Remarks: Myeloma cells with spleen cells from Balb/c mice.

Isotype: IgG1

Information d'application

Indications d'application: Studies of platelet functions. Identification of gpIIb. Immunohistochemistry on frozen sections or cell smears: 1: 50-1: 100 dilution. Fluorescence Microscopy or Flow Cytometry (20 l/10^6 platelets/test).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41 / ITGA2B

Sujet: The CD41 antigen (platelet GPIIb, alpha IIb integrin) is a Glycoprotein composed of 2 chains, GPIIb alpha (120 kDa) and GPIIb beta (23 kDa), linked by one disulfide bond. (1) CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. The structure and role of the complex CD41/CD61 in hemostasis is reviewed in Ref.2. CD41 is expressed by platelets, Megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the Megakaryocytic lineage. (3) It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on Human Leucocyte Differentiation Antigens in Boston, in 1993.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

ID gène: 9606

UniProt: P08514

Pathways: Integrin Complex