Mre11 anticorps (AA 575-600)

N° du produit ABIN129647

N° du produit (Fournisseur): 600-401-872

L’anticorps Lapin Polyclonal anti-Mre11 a été validé pour WB, ELISA et ChIP. Il convient pour détecter Mre11 dans des échantillons de Saccharomyces cerevisiae.

Aperçu rapide pour Mre11 anticorps (AA 575-600) (ABIN129647)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-Mre11 anticorps

Épitope: AA 575-600

N° du produit (Fournisseur): 600-401-872

Fournisseur: Rockland

Fonction: Mre11 Antibody

Réactivité croisée (Details): This affinity-purified antibody is directed against Saccharomyces cerevisiae Mre11 protein.

Attributs du produit: Synonyms: rabbit anti-Mre11 antibody, Double-strand break repair protein MRE11, DNA recombination and repair protein, Meiotic recombination 11

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 575-600 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity purified antibody has been tested for use in ELISA and by ChIP assay.  Specific conditions for reactivity should be optimized by the end user.

ChIP Dilution: User Optimized

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.19 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11

Sujet: Background: Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability.  Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function.  This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.

ID gène: 4361, 6323880

UniProt: P32829

Pathways: Réparation de l'ADN