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HMGB1 anticorps (AA 1-215)

HMGB1 Reactivité: Humain IF, IHC (p), ELISA, WB Hôte: Souris Monoclonal 1E6-E10 unconjugated
Pubmed (2 références)
N° du produit ABIN1326935
$534.67
Plus shipping costs $45.00
100 μg
Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables
  • Antigène Voir toutes HMGB1 Anticorps
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Épitope
    • 22
    • 16
    • 16
    • 14
    • 12
    • 11
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-215
    Reactivité
    • 175
    • 97
    • 94
    • 15
    • 13
    • 11
    • 10
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 153
    • 32
    • 2
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 146
    • 45
    Monoclonal
    Conjugué
    • 98
    • 18
    • 18
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp HMGB1 est non-conjugé
    Application
    • 136
    • 78
    • 50
    • 46
    • 30
    • 29
    • 27
    • 26
    • 17
    • 10
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
    Fonction
    Mouse monoclonal antibody raised against a full-length recombinant HMGB1.
    Séquence
    MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE

     Réactivité croisée
    Humain
    Immunogène
    HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1E6-E10
    Isotype
    IgG1 kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Product Quality tested by: Antibody Reactive Against Recombinant Protein.

    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kim, Ku, Bae: "Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLP-induced sepsis mice." dans: Journal of cellular physiology, Vol. 228, Issue 4, pp. 696-703, (2013) (PubMed).

    Lee, Ku, Kim, Bae: "Emodin-6-O-?-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 52, pp. 97-104, (2013) (PubMed).

  • Antigène
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Autre désignation
    HMGB1 (HMGB1 Produits)
    Synonymes
    HMG1, HMG3, SBP-1, DEF, HMG-1, Hmg1, amphoterin, p30, hmgb1, ik:tdsubc_1a5, wu:fb23c02, xx:tdsubc_1a5, zgc:56110, zgc:77104, hmg-1, hmg3, sbp-1, hmg1, HMGB1, Ac2-008, high mobility group box 1, high-mobility group box 1, high mobility group box 1a, high mobility group box 1 L homeolog, high mobility group protein B1, HMGB1, Hmgb1, hmgb1, hmgb1a, hmgb1.L, LOC100359149
    Sujet
    Full Gene Name: high-mobility group box 1
    Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1
    ID gène
    3146
    Pathways
    Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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