CD43 anticorps (Biotin)

N° du produit ABIN133167

Détail du produit anti-CD43 anticorps (Biotin)

Antigène: CD43 (SPN) (Sialophorin (SPN))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD43 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: Rat CD43

Immunogène: Rat thymocyte membrane . Fusion Partner: NS1/1 . Immunocyte Donor: BALB/c spleen

Clone: W3-13HLK

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: Biotin conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD43

Antigène: CD43 (SPN) (Sialophorin (SPN))

Autre désignation: CD43 (Leukosialin) (SPN Produits)

Synonymes: anticorps CD43, anticorps GALGP, anticorps GPL115, anticorps LSN, anticorps A630014B01Rik, anticorps Cd43, anticorps Galgp, anticorps Ly-48, anticorps Ly48, anticorps Lsn, anticorps Lsn1, anticorps gpL115, anticorps sialophorin, anticorps SPN, anticorps Spn

Sujet: Anti-rat CD43 monoclonal antibody recognizes a monomorphic determinant expressed on rat thymocytes, polymorphonuclear cells, plasma cells and stem cells, but not B lymphocytes or pre-B cells (1,3). The antigen is a heavily glycosylated glycoprotein of apparent molecular weight 95 kDa and has a high content of O-linked carbohydrate structures (3). This major glycoprotein of thymocytes and T lymphocytes is referred to by several names including leukocyte sialoglycoprotein and leukosialin. The carbohydrate structures of leukosialin account for approximately 60% of its weight (2). On thymocytes, this glycoprotein is the main target for binding of peanut lectin (4). This antibody is useful for labelling T but not B lymphocytes and in studies on stem cells since pre-B cells are not labelled while the multipotential stem cell is. It may also be used in analysis of NK cells (5) and in molecular studies of the sialoglycoprotein which it recognizes.

Pathways: Regulation of Leukocyte Mediated Immunity