CD45RC anticorps

N° du produit ABIN133289

Détail du produit anti-CD45RC anticorps

Antigène: CD45RC

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD45RC est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: Rat CD45RC

Purification: Purified

Immunogène: Phytohaemagglutinin-activated rat lymph node cells . FUSION PARTNER: P3-NSI-1-Ag4 (NS1/1) . IMMUNOCYTE DONOR: BALB/c Spleen

Clone: OX-22

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/ml

Stock: 4 °C

Détails sur CD45RC

Antigène: CD45RC

Autre désignation: CD45RC (CD45RC Produits)

Synonymes: anticorps CD45, anticorps L-CA, anticorps Lca, anticorps RT7, anticorps T200, anticorps protein tyrosine phosphatase, receptor type, C, anticorps Ptprc

Sujet: Rat Leukocyte Common Antigen has been shown to exist in different forms on different lymphoid cell types. Rat L-CA on thymocytes gives one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa and B cells one broad band at 240 kDa. T helper and T cytotoxic cell subsets show the same 4 bands with some differences in the proportions of each. ABIN133289reacts with the high molecular weight form of the leukocyte common antigen (2) which includes the 240 kDa form on B cells as well as a subfraction of the 190, 200 and 220 kDa forms, but not with the 180 kDa form of T cells or thymocytes. (5) Thus, ABIN133289reacts with B cells, cytotoxic T cells and helper cells for T cell responses but not with thymocytes or helper T cells for in vivo antibody responses. (5) Consequently, this antibody can be used to identify B cells, all CD8+ve T cells, 75% CD4+ve T cells and 50% bone marrow cells. This, antibody also divides rat CD4+ve T cells into two phenotypically distinct populations differing in their helper activities (6,7).