IL12 anticorps

N° du produit ABIN1383952

Cet anticorps Souris Monoclonal détecte spécifiquement IL12 dans ELISA, FACS et ELISpot. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour IL12 anticorps (ABIN1383952)

Antigène: IL12 (Interleukin 12 (IL12))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL12 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), ELISpot

Clone: B-P24

Détail du produit anti-IL12 anticorps

Specificité: Recognises both natural and recombinant p40 subunit alone and in its IL-12 form (associated with p35) and in its IL-23 form (associated with p19)

Purification: Ion exchange chromatography

Stérilité: 0.22 μm filtered

Immunogène: Recombinant human IL-12,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Références pour anticorps anti-IL12 (ABIN1383952)

Nagai, Devergne, Mueller, Perkins, van Seventer, van Seventer: "Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation" dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5233-43, (2003) (PubMed).

Détails sur IL12

Antigène: IL12 (Interleukin 12 (IL12))

Autre désignation: IL-12p40+p70

Sujet: IL-12/IL23p40, IL-12p70

Pathways: Signalistation JAK/STAT, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome