CLEC4E anticorps (AA 51-150)

N° du produit ABIN1385725

Cet anticorps Lapin Polyclonal détecte spécifiquement CLEC4E dans WB, ELISA, FACS, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour CLEC4E anticorps (AA 51-150) (ABIN1385725)

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLEC4E est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CLEC4E anticorps

Épitope: AA 51-150

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CLEC4E (ABIN1385725)

He, Xu, Li, Guo, Hu, Guo, Tang, Chen, Zhang, Tang, Zhang: "Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats." dans: Stroke, Vol. 46, Issue 8, pp. 2277-86, (2015) (PubMed).

Détails sur CLEC4E

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Autre désignation: CLEC 4E

Sujet:

Synonyms: C type lectin domain family 4 member E, C type lectin superfamily member 9, C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLC4E_HUMAN, CLEC 4E, CLEC4E Clec4e, CLECSF9, Macrophage inducible C type lectin, Macrophage-inducible C-type lectin, MINCLE.

Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

ID gène: 26253