CLEC4E anticorps (AA 41-219) (HRP)

N° du produit ABIN7146080

Détail du produit anti-CLEC4E anticorps (HRP)

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Épitope: AA 41-219

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLEC4E est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CLEC4E

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Autre désignation: CLEC4E (CLEC4E Produits)

Synonymes: anticorps CLECSF9, anticorps MINCLE, anticorps C86253, anticorps Clecsf9, anticorps Mincle, anticorps CLEC4E, anticorps C-type lectin domain family 4 member E, anticorps C-type lectin domain family 4, member e, anticorps C-type lectin domain family 4, member E, anticorps CLEC4E, anticorps Clec4e, anticorps LOC611538

Sujet:

Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6\\\'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Aliases: C type lectin domain family 4 member E antibody, C type lectin superfamily member 9 antibody, C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody, C-type lectin domain family 4 member E antibody, C-type lectin superfamily member 9 antibody, CLC4E_HUMAN antibody, CLEC 4E antibody, Clec4e antibody, CLECSF9 antibody, Macrophage inducible C type lectin antibody, Macrophage-inducible C-type lectin antibody, MINCLE antibody

UniProt: Q9ULY5