PTPRR anticorps (AA 165-270)

N° du produit ABIN1385754

Détail du produit anti-PTPRR anticorps

Antigène: PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))

Épitope: AA 165-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCPTP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PTPRR

Antigène: PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))

Autre désignation: PCPTP1 (PTPRR Produits)

Synonymes: anticorps EC-PTP, anticorps PCPTP1, anticorps PTP-SL, anticorps PTPBR7, anticorps PTPRQ, anticorps Pcptp1, anticorps ec-ptp, anticorps pcptp1, anticorps ptp-sl, anticorps ptpbr7, anticorps PTPRR, anticorps Gmcp1, anticorps RPTPRR, anticorps mPTP213, anticorps protein tyrosine phosphatase, receptor type R, anticorps protein tyrosine phosphatase, receptor type, R, anticorps protein tyrosine phosphatase, receptor type R L homeolog, anticorps protein tyrosine phosphatase, receptor type, r, anticorps receptor-type tyrosine-protein phosphatase R, anticorps PTPRR, anticorps Ptprr, anticorps ptprr.L, anticorps ptprr, anticorps LOC100715069

Sujet:

Synonyms: Ch-1PTPase, Ch1 PTPase, DKFZp781C1038, EC PTP, ECPTP, NC PTPCOM1, NC-PTPCOM1, Protein tyrosine phosphatase Cr1PTPase precursor, Protein tyrosine phosphatase NC PTPCOM1, Protein tyrosine phosphatase PCPTP1, Protein tyrosine phosphatase receptor type R, Protein-tyrosine phosphatase PCPTP1, PTP SL, PTPBR7, PTPRQ, PTPRR, PTPRR_HUMAN, PTPSL, R-PTP-R, Receptor type tyrosine protein phosphatase R, Receptor-type tyrosine-protein phosphatase R.

Background: The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localized to the cell membrane, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm.