Dihydrofolate Reductase anticorps

N° du produit ABIN1387277

L’anticorps Lapin Polyclonal anti-Dihydrofolate Reductase a été validé pour WB, IHC (p), IF (p) et FACS. Il convient pour détecter Dihydrofolate Reductase dans des échantillons de Humain.

Aperçu rapide pour Dihydrofolate Reductase anticorps (ABIN1387277)

Antigène: Dihydrofolate Reductase (DHFR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dihydrofolate Reductase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Détail du produit anti-Dihydrofolate Reductase anticorps

Purification: purified by Protein A and peptide affinity chromatography

Immunogène: KLH conjugated synthetic peptide derived from human DHFR

Isotype: IgG

Information d'application

Indications d'application: WB (1:100-500),IHC-P (1:100-500),FACS (1:50-200),IF (p) (1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C for 12 months

Date de péremption: 12 months

Détails sur Dihydrofolate Reductase

Antigène: Dihydrofolate Reductase (DHFR)

Autre désignation: DHFR

Sujet: DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.

Poids moléculaire: 21kDa

ID gène: 1719

HGNC: 0

Pathways: Mitotic G1-G1/S Phases