Geminin anticorps (AA 110-142)

N° du produit ABIN1387623

Détail du produit anti-Geminin anticorps

Antigène: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Épitope: AA 110-142

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Geminin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Geminin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Geminin

Antigène: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Autre désignation: Geminin (GMNN Produits)

Synonymes: anticorps CG3183, anticorps Dm Geminin, anticorps Dm geminin, anticorps Dmel\\CG3183, anticorps Gem, anticorps Geminin, anticorps anon-WO0257455.1, anticorps gem, anticorps l(2)k14019, anticorps v(2)k09107, anticorps sb:cb254, anticorps zgc:66217, anticorps GB16871, anticorps GMNN, anticorps geminin, anticorps dyak_GLEANR_833, anticorps DyakGE24654, anticorps GE24654, anticorps LOC100049517, anticorps AW546347, anticorps geminin, DNA replication inhibitor, anticorps CG3183 gene product from transcript CG3183-RA, anticorps geminin, anticorps GE24654 gene product from transcript GE24654-RA, anticorps GMNN, anticorps geminin, anticorps gmnn, anticorps LOC410093, anticorps Dyak\geminin, anticorps Gmnn

Sujet:

Synonyms: Gem, Geminin, GMNN

Background: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.

ID gène: 51053

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication