DOK6 anticorps (AA 1-100) (Alexa Fluor 555)

N° du produit ABIN1389065

Détail du produit anti-DOK6 anticorps (Alexa Fluor 555)

Antigène: DOK6 (Docking Protein 6 (DOK6))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK6 est conjugé à/à la Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DOK6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DOK6

Antigène: DOK6 (Docking Protein 6 (DOK6))

Autre désignation: DOK6 (DOK6 Produits)

Synonymes: anticorps DOK5L, anticorps HsT3226, anticorps Dok-6, anticorps RGD1564376, anticorps docking protein 6, anticorps DOK6, anticorps Dok6

Sujet:

Synonyms: Docking protein 5, Docking protein 5 like, Docking protein 6, DOK 6, DOK6, DOK-6, DOK5, DOK 5, DOK-5, DOK5L, Downstream of tyrosine kinase 6, HsT3226, MGC20785, Protein dok 5, DOK6_HUMAN.

Background: The downstream of kinase family (Dok-1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.