Syntaxin 6 anticorps (AA 161-255) (Alexa Fluor 350)

N° du produit ABIN1390221

Détail du produit anti-Syntaxin 6 anticorps (Alexa Fluor 350)

Antigène: Syntaxin 6 (STX6)

Épitope: AA 161-255

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Syntaxin 6 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Syntaxin 6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Syntaxin 6

Antigène: Syntaxin 6 (STX6)

Autre désignation: Syntaxin 6 (STX6 Produits)

Synonymes: anticorps CG7736, anticorps CT23545, anticorps Dm Syx6, anticorps DmSyx6, anticorps Dmel\\CG7736, anticorps SYN6, anticorps SYX6/10, anticorps Syx, anticorps MGC78971, anticorps MGC132090, anticorps STX6, anticorps fb51b08, anticorps wu:fb51b08, anticorps zgc:110658, anticorps si:dkey-121a11.2, anticorps LOC734102, anticorps Syx6, anticorps Bmsyx6, anticorps Syntaxin-6, anticorps 2310039E05Rik, anticorps 2410005I16Rik, anticorps AA437559, anticorps AI415714, anticorps AI845861, anticorps Syntaxin 6, anticorps syntaxin 6 L homeolog, anticorps syntaxin 6, anticorps Syx6, anticorps stx6.L, anticorps STX6, anticorps stx6, anticorps Stx6

Sujet:

Synonyms: STX 6, STX6, STX-6, STX6_HUMAN, Syntaxin-6, Syntaxin6.

Background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.

Pathways: Synaptic Vesicle Exocytosis