CTRP5 anticorps (AA 191-243) (Alexa Fluor 350)

N° du produit ABIN1392921

Détail du produit anti-CTRP5 anticorps (Alexa Fluor 350)

Antigène: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Épitope: AA 191-243

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTRP5 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CTRP5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CTRP5

Antigène: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Autre désignation: CTRP5 (C1QTNF5 Produits)

Synonymes: anticorps C1QTNF5, anticorps wu:fb02c10, anticorps wu:fb02f05, anticorps zgc:112378, anticorps CTRP5, anticorps Ctrp5, anticorps C1q and tumor necrosis factor related protein 5, anticorps C1q and TNF related 5, anticorps C1QTNF5, anticorps c1qtnf5, anticorps C1qtnf5

Sujet:

Synonyms: C1q and tumor necrosis factor related protein 5, C1QTNF5, Complement C1q tumor necrosis factor related protein 5 precursor, LORD, C1QT5_HUMAN.

Background: Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch?s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.

ID gène: 114902

UniProt: Q9BXJ0