CTRP5 anticorps (AA 191-243) (Biotin)
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- Antigène Voir toutes CTRP5 (C1QTNF5) Anticorps
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
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Épitope
- AA 191-243
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CTRP5 est conjugé à/à la Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CTRP5
- Isotype
- IgG
- Top Product
- Discover our top product C1QTNF5 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
- Autre désignation
- CTRP5 (C1QTNF5 Produits)
- Synonymes
- anticorps C1QTNF5, anticorps wu:fb02c10, anticorps wu:fb02f05, anticorps zgc:112378, anticorps CTRP5, anticorps Ctrp5, anticorps C1q and tumor necrosis factor related protein 5, anticorps C1q and TNF related 5, anticorps C1QTNF5, anticorps c1qtnf5, anticorps C1qtnf5
- Sujet
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Synonyms: C1q and tumor necrosis factor related protein 5, C1QTNF5, Complement C1q tumor necrosis factor related protein 5 precursor, LORD, C1QT5_HUMAN.
Background: Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch?s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.
- ID gène
- 114902
- UniProt
- Q9BXJ0
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