DACT3 anticorps (AA 575-629) (Alexa Fluor 350)

N° du produit ABIN1393617

Détail du produit anti-DACT3 anticorps (Alexa Fluor 350)

Antigène: DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))

Épitope: AA 575-629

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DACT3 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DACT3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DACT3

Antigène: DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))

Autre désignation: DACT3 (DACT3 Produits)

Synonymes: anticorps EG666671, anticorps naa-3, anticorps DAPPER3, anticorps RRR1, anticorps RGD1563892, anticorps dishevelled binding antagonist of beta catenin 3, anticorps dishevelled-binding antagonist of beta-catenin 3, anticorps DACT3, anticorps Dact3

Sujet:

Synonyms: Antagonist of beta-catenin Dapper homolog 3, Arginine rich region 1, Arginine rich region 1 protein, Arginine-rich region 1 protein, Dact3 antibody, DACT3_HUMAN, Dapper antagonist of beta catenin 3, Dapper antagonist of beta catenin homolog 3 Xenopus laevis, Dapper homolog 3, Dapper3, Dpr3 antibodyRRR1, RRR1, Thymus expressed gene 3 like.

Background: Dapper3 is a 629 amino acid protein and mammalian homolog of the Xenopus laevis protein dapper. As a member of the dapper family, Dapper3 plays a role in postnatal brain development and contains a C-terminal PDZ-binding motif that facilitates interaction with the PDZ domains of DSH (Dishevelled) family proteins. As the predominant dapper family member found in adult brain, Dapper 3 localizes to hippocampus, Purkinje cell layer and every layer of the dorsal forebrain and cerebral cortex and is also found in the developing murine central nervous system. Dapper3 is also expressed in uterus, ventral somites, branchial arch mesenchyme, aortic sac, aortic arches, limb bud mesenchyme and craniofacical mesenchyme. Mapping to human chromosome 19q13.32, Dapper3 has been identified as a negative regulator of Wnt/beta-catenin signaling in colorectal cancer.