GABARAP anticorps (AA 11-117) (Alexa Fluor 488)

N° du produit ABIN1395052

Détail du produit anti-GABARAP anticorps (Alexa Fluor 488)

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Épitope: AA 11-117

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABARAP est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GABARAP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GABARAP

Antigène: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Autre désignation: GABARAP (GABARAP Produits)

Synonymes: anticorps GABARAP, anticorps ATG8A, anticorps GABARAP-a, anticorps MM46, anticorps gabarap, anticorps mg:bb02b03, anticorps GABA type A receptor-associated protein, anticorps gamma-aminobutyric acid receptor-associated protein, anticorps GABA(A) receptor-associated protein a, anticorps gamma-aminobutyric acid receptor associated protein, anticorps GABARAP, anticorps LOC5568843, anticorps Gabarap, anticorps gabarapa

Sujet:

Synonyms: ATG8A, FLC 3B, FLC3B, FLJ25768, GABAA receptor associated protein, GABAA receptor-associated protein, GABARAP a, GABARAP, Gamma aminobutyric acid receptor associated protein, Gamma-aminobutyric acid receptor-associated protein, GBRAP_HUMAN, MGC120154, MGC120155, MM 46, MM46.

Background: In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA ) and metabotropic (GABAB ) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.

Pathways: Autophagy