BRP44 anticorps (AA 21-100) (Alexa Fluor 350)

N° du produit ABIN1399023

Détail du produit anti-BRP44 anticorps (Alexa Fluor 350)

Antigène: BRP44 (Brain Protein 44 (BRP44))

Épitope: AA 21-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRP44 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BRP44

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BRP44

Antigène: BRP44 (Brain Protein 44 (BRP44))

Autre désignation: BRP44 (BRP44 Produits)

Synonymes: anticorps BRP44, anticorps 0610006C01Rik, anticorps 2010002I07Rik, anticorps 2610205H19Rik, anticorps AA108335, anticorps Brp44, anticorps ESTM43, anticorps brp44, anticorps wu:fb22b02, anticorps wu:fb22g07, anticorps zgc:56391, anticorps zgc:86614, anticorps MGC53394, anticorps DKFZp459F1815, anticorps RGD1563422, anticorps mitochondrial pyruvate carrier 2, anticorps mitochondrial pyruvate carrier 2 S homeolog, anticorps uncharacterized protein, anticorps MPC2, anticorps Mpc2, anticorps mpc2, anticorps mpc2.S, anticorps LOC706595, anticorps LOC100285678

Sujet:

Synonyms: ESTM43, MGC125753, BR44_HUMAN, Brain protein 44, BRP44, DKFZp564B167, MGC125752, rCG_46381, RGD1563422, RP1-295C6.1.

Background: BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

ID gène: 25874

Pathways: L'effet Warburg