TRPM5 anticorps (Alexa Fluor 350)

N° du produit ABIN1400529

Détail du produit anti-TRPM5 anticorps (Alexa Fluor 350)

Antigène: TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM5 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRPM5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TRPM5

Antigène: TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))

Autre désignation: TRPM5 (TRPM5 Produits)

Synonymes: anticorps LTRPC5, anticorps MTR1, anticorps 9430099A16Rik, anticorps LTrpC-5, anticorps Ltrpc5, anticorps Mtr1, anticorps transient receptor potential cation channel subfamily M member 5, anticorps transient receptor potential cation channel, subfamily M, member 5, anticorps TRPM5, anticorps Trpm5, anticorps trpm5

Sujet:

Synonyms: MLSN1 and TRP related gene 1, MLSN1 and TRP related gene 1 protein, MLSN1 and TRP-related, MLSN1- and TRP-related gene 1 protein, MTR1, Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5 , Transient receptor potential cation channel subfamily M member 5, Transient receptor potential cation channel, subfamily M, member 5, Trpm5, TRPM5 transient receptor potential cation channel, subfamily M, member 5, TRPM5_HUMAN, 9430099A16Rik, Long transient receptor potential channel 5, LTrpC-5, LTrpC5.

Background: Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

ID gène: 29850