SERPINA10 anticorps (Alexa Fluor 350)

N° du produit ABIN1401471

Détail du produit anti-SERPINA10 anticorps (Alexa Fluor 350)

Antigène: SERPINA10 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINA10 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZPI/SERPINA10

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SERPINA10

Antigène: SERPINA10 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10))

Autre désignation: SERPINA10 (SERPINA10 Produits)

Synonymes: anticorps PZI, anticorps ZPI, anticorps Rasp1, anticorps SERPINA10, anticorps DKFZp469K045, anticorps si:dkey-85n7.5, anticorps serpin family A member 10, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, anticorps serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a, anticorps SERPINA10, anticorps Serpina10, anticorps serpina10a

Sujet:

Synonyms: Protein Z dependent protease inhibitor, Protein Z dependent protease inhibitor precursor, Protein Z-dependent protease inhibitor, PZ dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, serine or cysteine proteinase inhibitor clade A alpha 1 antiproteinase antitrypsin member 10 , Serpin A10, Serpin peptidase inhibitor clade A alpha 1 antiproteinase antitrypsin member 10, SERPINA 10, SERPINA10, ZPI, ZPI_HUMAN.

Background: ZPI, also known as SERPINA10 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) or PZI, is a 444 amino acid secreted protein that functions as a Protein Z-dependent protease inhibitor. Expressed by the liver, ZPI is secreted into the plasma where, in the presence of calcium, Protein Z and phospholipids, it inhibits the activated pro-coagulation factors X and XI (Factor X and Factor XI). This inhibition helps properly regulate intravenous blood clotting. ZPI, a member of the serpin protein family, contains five potential N-linked glycosylation sites and a tyrosine at position 387 which, when disrupted, renders ZPI inactive. Defects in the gene encoding ZPI may increase susceptibility to venous thrombosis, the formation of blood clots within a vein.

ID gène: 51156