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NAT8B anticorps (AA 221-227) (Cy7)

NAT8B Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1410078
  • Antigène Voir toutes NAT8B Anticorps
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    Épitope
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 221-227
    Reactivité
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 19
    • 1
    Lapin
    Clonalité
    • 19
    • 1
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NAT8B est conjugé à/à la Cy7
    Application
    • 19
    • 12
    • 12
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NAT8B
    Isotype
    IgG
    Top Product
    Discover our top product NAT8B Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    Autre désignation
    NAT8B (NAT8B Produits)
    Synonymes
    anticorps EG434057, anticorps Cml1, anticorps Cml6, anticorps Nat8, anticorps RGD621605, anticorps CML2, anticorps Hcml2, anticorps NAT8BP, anticorps N-acetyltransferase 8B, anticorps N-acetyltransferase 8B, pseudogene, anticorps N-acetyltransferase 8B (putative, gene/pseudogene), anticorps NAT8B, anticorps Nat8b-ps, anticorps Nat8b
    Sujet

    Synonyms: Camello like protein 2, Camello-like protein 2, CML2, Hcml2, N acetyltransferase 8B, NAT8B, NAT8B_HUMAN, NAT8BP, Probable N acetyltransferase 8B, Probable N-acetyltransferase 8B.

    Background: Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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