CTNND2 anticorps (AA 951-1050) (HRP)

N° du produit ABIN1410590

Détail du produit anti-CTNND2 anticorps (HRP)

Antigène: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Épitope: AA 951-1050

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNND2 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human delta 2 Catenin

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CTNND2

Antigène: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Autre désignation: CTNND2/delta 2 Catenin (CTNND2 Produits)

Synonymes: anticorps CTNND2, anticorps Catnd2, anticorps Nprap, anticorps neurojugin, anticorps GT24, anticorps NPRAP, anticorps ctnnd2, anticorps si:dkey-40c17.4, anticorps catenin delta 2, anticorps delta-catenin, anticorps catenin delta-2, anticorps catenin (cadherin associated protein), delta 2, anticorps catenin (cadherin-associated protein), delta 2b, anticorps CTNND2, anticorps BACOIKO001_27, anticorps LOC100070792, anticorps Ctnnd2, anticorps ctnnd2b

Sujet:

Synonyms: Catenin cadherin associated protein delta 2, Catenin delta 2, Catenin delta-2, CTND2_HUMAN, CTNND 2, CTNND2, Delta catenin, Delta-catenin, GT 24, GT24, Neural plakophilin related arm repeat protein, Neural plakophilin related armadillo repeat protein, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAP

Background: The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.