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CTRP5 anticorps (AA 191-243) (Cy7)

C1QTNF5 Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1410816
  • Antigène Voir toutes CTRP5 (C1QTNF5) Anticorps
    CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-243
    Reactivité
    • 20
    • 17
    • 2
    Souris
    Hôte
    • 22
    • 10
    • 2
    Lapin
    Clonalité
    • 33
    • 1
    Polyclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTRP5 est conjugé à/à la Cy7
    Application
    • 27
    • 12
    • 12
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CTRP5
    Isotype
    IgG
    Top Product
    Discover our top product C1QTNF5 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
    Autre désignation
    CTRP5 (C1QTNF5 Produits)
    Synonymes
    anticorps C1QTNF5, anticorps wu:fb02c10, anticorps wu:fb02f05, anticorps zgc:112378, anticorps CTRP5, anticorps Ctrp5, anticorps C1q and tumor necrosis factor related protein 5, anticorps C1q and TNF related 5, anticorps C1QTNF5, anticorps c1qtnf5, anticorps C1qtnf5
    Sujet

    Synonyms: C1q and tumor necrosis factor related protein 5, C1QTNF5, Complement C1q tumor necrosis factor related protein 5 precursor, LORD, C1QT5_HUMAN.

    Background: Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch?s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.

    ID gène
    114902
    UniProt
    Q9BXJ0
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