GRIK2 anticorps (AA 164-270) (Cy5.5)

N° du produit ABIN1412501

Détail du produit anti-GRIK2 anticorps (Cy5.5)

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Épitope: AA 164-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK2 est conjugé à/à la Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GRIK2/GLR6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GRIK2

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Autre désignation: GRIK2/GLR6 (GRIK2 Produits)

Synonymes: anticorps GRIK5, anticorps eaa4, anticorps glr6, anticorps gluk6, anticorps glur6, anticorps grik2, anticorps mrt6, anticorps GluR6, anticorps grik2-A, anticorps EAA4, anticorps GLR6, anticorps GLUK6, anticorps GLUR6, anticorps GluK2, anticorps MRT6, anticorps AW124492, anticorps Glur-6, anticorps Glur6, anticorps Glurbeta2, anticorps GRIK2, anticorps glutamate ionotropic receptor kainate type subunit 2, anticorps glutamate receptor, ionotropic, kainate 2 L homeolog, anticorps glutamate receptor, ionotropic, kainate 2, anticorps glutamate receptor, ionotropic, kainate 2 (beta 2), anticorps GRIK2, anticorps grik2.L, anticorps grik2, anticorps Grik2

Sujet:

Synonyms: CSNB 1B, DKFZp686H1993, EAA4, Excitatory amino acid receptor 4, G protein coupled receptor family C group 1 member F, GLR 6, GLR6, GLUR 6, GluR-6, GLUR6, Glutamate receptor 6, Glutamate receptor, Glutamate receptor ionotropic kainate 2, Gprc 1f, Gprc1f, GRIK 2, GRIK2, GRIK2 protein, GRIK2_HUMAN, GRM 6, ionotropic kainate 2.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity