SERPINE2 anticorps (AA 301-398) (HRP)

N° du produit ABIN1422868

Détail du produit anti-SERPINE2 anticorps (HRP)

Antigène: SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))

Épitope: AA 301-398

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINE2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GDN/SERPINE2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SERPINE2

Antigène: SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))

Autre désignation: GDN (SERPINE2 Produits)

Synonymes: anticorps GDN, anticorps GDNPF, anticorps PI-7, anticorps PI7, anticorps PN-1, anticorps PN1, anticorps PNI, anticorps SERPINE2, anticorps MGC143011, anticorps Gdnpn1, anticorps Pn-1, anticorps Spin4, anticorps B230326M24Rik, anticorps PAI-1, anticorps Spi4, anticorps zgc:55929, anticorps serpin family E member 2, anticorps serine (or cysteine) peptidase inhibitor, clade E, member 2, anticorps serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, anticorps SERPINE2, anticorps serpine2, anticorps Serpine2

Sujet:

Synonyms: Glia derived nexin, Protease inhibitor 7, GDN, GDN_HUMAN, Glia-derived nexin, P17 antibody Peptidase inhibitor 7, Pi-7, Plasminogen activator inhibitor type 1, member 2, PN-1, PN1, PNI, Protease nexin 1, Protease nexin I, Serpin E2, Serpin peptidase inhibitor, clade E nexin, plasminogen activator inhibitor type 1, member 2, SERPINE 2, Serpine2.

Background: The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, including thrombin, urokinase, plasminogen activators (PA) and plasmin. It is involved in tissue remodeling, cellular invasiveness, matrix degradation and tumor growth. PN-1 expression is abundant in the nervous system, where it inhibits thrombin, thereby playing a role in neural injury and repair processes. An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimer??s disease.

ID gène: 5270

UniProt: P07093